Gamete Donation
Gamete Donation
Oocyte donation (OD) is defined as the assisted reproduction technique (ART) in which the female gamete is provided by a different woman than the one who will receive it or the resulting embryo.
Oocyte Donation
Oocyte donation (OD) is defined as the assisted reproduction technique (ART) in which the female gamete is provided by a different woman than the one who will receive it or the resulting embryo.
- Ovarian agenesis
- Primary ovarian failure (Swyer syndrome, Turner syndrome)
- Age-related declined ovarian reserve
- Premature ovarian failure (secondary)
- Radiotherapy or chemotherapy
- Surgical removal of ovary
- Multiple IVF failures
- Chromosomal abnormality in karyotype of the woman
- History of initially chromosomally abnormal children
- Unaccessible ovaries for ovum pick-up, severe adhesion pelvic disease
- Recurrent pregnancy loss
- Ovarian agenesis
- Primary ovarian failure (Swyer syndrome, Turner syndrome)
- Age-related declined ovarian reserve
- Premature ovarian failure (secondary)
- Radiotherapy or chemotherapy
- Surgical removal of ovary
- Multiple IVF failures
- Chromosomal abnormality in karyotype of the woman
- History of initially chromosomally abnormal children
- Unaccessible ovaries for ovum pick-up, severe adhesion pelvic disease
- Recurrent pregnancy loss
- Must be free from HIV, hepatitis B & C, hypertension, diabetes, sexually transmitted diseases, and common genetic disorders such as thalassemia
- Blood group and Rh status must be recorded
- Details such as height, weight, age, and family history of genetic disorders must be documented
- Donor age must be more than 21 and less than 35 years
Sperm Donation
Indications of Donor Sperm
- Non-obstructive azoospermia
- Recurrent IVF failures due to poor sperm quality
- High risk of genetic abnormality transmission
- Infectious disease in male partner
- Single mother desirous of child
- Homosexual couple desirous of child
- Severe Rh isoimmunization
- Severe oligo-asthenospermia not suitable for ICSI
Requirement for a Sperm Donor
- Must be free from HIV, hepatitis B & C, hypertension, diabetes, sexually transmitted diseases, and common genetic disorders such as thalassemia
- Age of donor must be between 21 and 45 years
- Semen analysis must be normal as per WHO guidelines for ART
- Blood group and Rh status must be recorded
- Information such as height, weight, age, education, profession, skin and eye color, medical history (including psychiatric disorders), and family history of genetic disorders must be documented in an appropriate proforma