nirmiticlinic

Best IUI Centre in PCMC

Best IUI Centre in PCMC

Intrauterine Insemination (IUI) is a simple, effective, and affordable first-line fertility treatment for infertile couples. In this procedure, specially prepared sperm with good quality is placed directly into the uterus at the time of ovulation to improve the chances of fertilization.
Nirmiti Clinic is recognized as one of the Best IUI Centres in PCMC, offering advanced and ethical fertility care.

  • Detailed medical history of both partners.
    Physical examination of both partners
  • Semen analysis of male partner
  • Tests for anti-sperm antibodies
  • Confirmation of ovulation (Follicular USG, Day-21 progesterone)
  • Confirmation of tubal patency (HSG, Laparoscopy, HyCoSy)
  • Evaluation of uterine cavity abnormalities
Careful patient selection is crucial for successful IUI outcomes.
Indications include:
  • Ejaculatory failure both partners
  • Cervical factors
  • Tests for anti-sperm antibodies
  • Male subfertility
  • Immunological infertility
  • Unexplained infertility
  • PCOS
  • HIV discordant couples
Not suitable in cases of:
  • Bilateral tubal block
  • Severe pelvic infections
  • Severe oligoasthenoteratozoospermia

Equipment includes:
  • Laminar air flow unit
  • Microscopy setup
  • Incubator
  • Centrifuge
Optional facilities:
  • Semen analysis
  • Semen freezing and storage
  • Warming equipment

According to ART guidelines in India, an IUI center should be a Level-2 facility with advanced diagnostic and treatment infrastructure.

Facilities required:
  • Immunological testing
  • Sperm function tests
  • TVS and follicular monitoring
  • Hysteroscopy / Laparoscopy
Essential equipment:
  • Laminar air flow unit
  • Sperm counting chambers
  • Microscopy
  • Incubator
  • Centrifuge
  • Ovarian stimulation (natural or stimulated cycle)
  • Follicular and endometrial monitoring
  • Timed insemination based on ovulation
  • Ultrasound and hormonal monitoring
  • HCG trigger when follicle 18 mm
Common methods include:
  • Swim-up technique
  • Density gradient centrifugation

 

  • Wash and centrifugation

Proper sperm preparation improves capacitation and removes debris and bacteria.

Success rates vary between 5% to 30% per cycle, depending on:
  • Cause of infertility
  • Female age
  • Duration of infertility
  • Sperm quality
  • Type of stimulation
Possible complications:
  • Treatment failure
  • Infection or bleeding
  • Multiple pregnancy
  • OHSS
  • Ectopic pregnancy
  • Semen sample preparation and freezing
  • Controlled cooling and storage
  • Thawing in water bath before use
  • Motility assessment before insemination
Success rates vary between 5% to 30% per cycle, depending on:
  • Cause of infertility
  • Female age
  • Duration of infertility
  • Sperm quality
  • Type of stimulation
Possible complications:
  • Treatment failure
  • Infection or bleeding
  • Multiple pregnancy
  • OHSS
  • Ectopic pregnancy
  • Ovulation confirmation
  • Semen collection and preparation
  • Patient counseling
  • Aseptic insemination procedure
  • Post-procedure rest

IUI can be safely performed in HIV discordant couples using sperm washing techniques.
Global studies have shown no transmission risk when proper protocols are followed.

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